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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFAS
All Species:
22.42
Human Site:
Y538
Identified Species:
41.11
UniProt:
O15067
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15067
NP_036525
1338
144724
Y538
D
P
A
G
A
I
I
Y
T
S
R
F
Q
L
G
Chimpanzee
Pan troglodytes
XP_511854
1397
150781
Y597
D
P
A
G
A
I
I
Y
T
S
R
F
Q
L
G
Rhesus Macaque
Macaca mulatta
XP_001112405
1335
144369
Y538
D
P
A
G
A
I
I
Y
T
S
R
F
Q
L
G
Dog
Lupus familis
XP_850167
1368
147436
Y538
D
P
A
G
A
V
I
Y
T
S
R
F
Q
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUR0
1337
144611
Y538
D
P
E
G
A
I
I
Y
T
S
R
F
Q
L
G
Rat
Rattus norvegicus
NP_001099261
1271
136879
L496
Q
E
S
N
A
L
L
L
R
P
S
D
R
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038667
1314
142462
Y534
E
P
A
G
A
V
I
Y
T
E
K
F
K
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35421
1354
148067
F547
G
F
A
G
A
V
I
F
S
K
E
F
Q
L
G
Honey Bee
Apis mellifera
XP_625036
1243
138433
F500
E
P
E
G
A
V
I
F
A
K
K
F
E
L
G
Nematode Worm
Caenorhab. elegans
Q19311
1343
148611
K530
E
G
C
G
V
T
V
K
S
D
T
F
Q
L
G
Sea Urchin
Strong. purpuratus
XP_781955
1205
129101
S487
T
K
K
S
R
I
V
S
N
P
V
D
L
D
L
Poplar Tree
Populus trichocarpa
XP_002315209
1377
150616
D591
Y
P
K
G
A
Q
I
D
I
R
A
I
V
I
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8D3
1387
151761
D602
Y
P
Q
G
A
E
I
D
I
R
A
V
V
V
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
97.1
87.5
N.A.
88.5
84
N.A.
N.A.
N.A.
N.A.
63.2
N.A.
50.5
50.1
47.5
52.4
Protein Similarity:
100
95.2
98
91.6
N.A.
92.8
88.6
N.A.
N.A.
N.A.
N.A.
75.1
N.A.
66
66.2
64.1
65.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
N.A.
N.A.
N.A.
60
N.A.
53.3
46.6
33.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
33.3
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
73.3
80
53.3
13.3
Percent
Protein Identity:
50.3
N.A.
N.A.
50.4
N.A.
N.A.
Protein Similarity:
65.2
N.A.
N.A.
65.3
N.A.
N.A.
P-Site Identity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
47
0
85
0
0
0
8
0
16
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
0
0
0
0
0
0
16
0
8
0
16
0
16
0
% D
% Glu:
24
8
16
0
0
8
0
0
0
8
8
0
8
0
0
% E
% Phe:
0
8
0
0
0
0
0
16
0
0
0
70
0
0
8
% F
% Gly:
8
8
0
85
0
0
0
0
0
0
0
0
0
0
85
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
39
77
0
16
0
0
8
0
8
0
% I
% Lys:
0
8
16
0
0
0
0
8
0
16
16
0
8
0
0
% K
% Leu:
0
0
0
0
0
8
8
8
0
0
0
0
8
62
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
70
0
0
0
0
0
0
0
16
0
0
0
0
0
% P
% Gln:
8
0
8
0
0
8
0
0
0
0
0
0
54
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
8
16
39
0
8
8
0
% R
% Ser:
0
0
8
8
0
0
0
8
16
39
8
0
0
0
0
% S
% Thr:
8
0
0
0
0
8
0
0
47
0
8
0
0
0
0
% T
% Val:
0
0
0
0
8
31
16
0
0
0
8
8
16
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _